Funded Grants

Mental health disorders impact one in four Canadians, yet our understanding of the brain and its relationship to mental illness is dwarfed by what we do not know.

While most forms of ALS occur in adulthood, mutations in the gene termed Serine Palmitoyltransferase Long Chain Base Subunit 1 (SPTLC1) arise in children.

Psychedelic drugs, known for their profound effects on perception, are showing promise as rapid and long-lasting treatments for depression.

Alzheimer’s Disease (AD) affects many people and leads to memory loss and cognitive decline. It is linked to brain inflammation and changes in proteins like GFAP, which is usually found in support cells called astrocytes.

Apathy (reduced goal-directed behaviour) is common in persons with dementia and is associated with lower quality of life, increased dependence and faster decline.

We discovered that approximately one fifth of people with the deadly brain tumour glioblastoma show age-related genetic changes in their blood cells called ‘clonal hematopoiesis’, or CHIP.

The International Spinal Cord Injury Biobank (ISCIB) is a multi-user biorepository with the mission of accelerating therapeutic development in traumatic spinal cord injury (SCI) through improved biological understanding of human injury, and the vision of serving as a global research resource where human SCI biospecimens are shared with researchers around the world.

There is an urgent need for research that deepens our understanding of human brain function and uses this knowledge to accelerate therapeutic breakthroughs related to brain dysfunction.

Glioblastoma (GBM) is the most common and deadly adult brain cancer.

Optogenetics, defined as a technique where light-sensitive genes are introduced into brain cells to control their activity with light, allows researchers to precisely control nerve cell communication thereby, transforming brain research.