Funded Grants

Research suggests that exercise can help improve brain health and decrease the risk of dementia, but there is variation in the benefit of different exercise interventions.

Alzheimer’s disease causes progressive neurological decline and substantially decreases the quality of life of the individuals with the disease and their caregivers.

One in six people worldwide will experience a stroke in their lifetime.

Each year, 1-2 million children in North America suffer a concussion.

Perinatal (around birth) stroke is devastating, because the effects are life-long.

Dr. Sasaki research aims to (1) determine the mechanisms by which maternal synthetic glucocorticoids (sGC) modifies gene networks in a preclinical guinea pig model and (2) determine the mechanism by which a single maternal treatment of sGC modifies gene networks in human cord blood at term deliveries.

Dr. Eid will test the hypothesis that the Trio gene is a central regulator of the development and maturation of cortical interneurons (INs) and that its loss underlies some genetic forms of epileptic encephalopathies (EE) by disrupting cortical network development and function.

Amblyopia (commonly known as “lazy eye”) is a common developmental visual disorder, caused by eye misalignment, unequal refractive error between two eyes, or visual deprivation, with lifelong consequences on learning and academic achievements that we do not fully understand. It affects 4.7% of Canadian children, and 22-41% of children do not respond to conventional treatment.

Medulloblastoma is a pediatric cancer of the brain and is the most common solid tumour in children.

Dr. Orlandi’s research seeks to investigate the effectiveness of 3D video-based method in early detection of motor impairment (MI), specifically looking at infants at risk of cerebral palsy (CP). The aims of this project are to: 1) develop a standardized protocol for 3D video recordings; and 2) develop a novel method for the automated General Movement Assessment (GMA) based on 3D video analysis to distinguish aytpical/typical general movements (GMs).