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Guy Rouleau , Montreal Neurological Hospital and Institute × Clear Filters

4 results found

Investigating the templated propagation and impact of pathogenic FUS in hiPSCs-derived cerebral organoids

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder that affects the human motor system, leading to muscle weakness and ultimately paralysis.

Project ongoing See Project & Researchers
Area of Research
Neurodegeneration
Competition
ALS Canada - Brain Canada Discovery Grants
Province
Québec
Start Date
2025

Investigating inhibition of TDP-43 propagation as a therapeutic strategy for ALS

It is not known why ALS is a rapidly progressing disease.

Project ongoing See Project & Researchers
Grant type
Team grants
Area of Research
Neurodegeneration
Competition
ALS Canada - Brain Canada Discovery Grants
Province
Québec
Start Date
2024

The Neuro’s Virtual Integrated Patient Platform

Patients with neurological disease are understandably frustrated by the lack of meaningful pharmacological treatments for even comparatively common pathologies such as Parkinson’s Disease.

Project ongoing See Project & Researchers
Grant type
Platform grants
Area of Research
Multiple
Competition
2021 Platform Support Grants
Province
Québec
Start Date
2022

Personalized medicine for Bipolar disorder: clinical lithium response as a guide to mode of action and biomarker discovery using human neurons and biofluids

Bipolar Disorder (BD) is a chronic psychiatric illness, ranking in the top 10 causes of disability and mortality worldwide, due to suicide and cardiovascular death.

Project ongoing See Project & Researchers
Grant type
Team grants
Area of Research
Mental Health
Competition
Bell Let's Talk - Brain Canada Mental Health Research Program
Province
Québec
Start Date
2022