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Christine Vande Velde , Université de Montréal × Clear Filters

5 results found

Stress granules: neuroprotective or neurotoxic in ALS pathogenesis?

ALS is a devastatingly fatal neurodegenerative disease with patients losing their ability to walk, talk, eat, and interact with their loved ones.

Project ongoing See Project & Researchers
Area of Research
Neurodegeneration
Competition
ALS Canada - Brain Canada Discovery Grants
Province
Québec
Start Date
2025

Relevance of stress granule dynamics to ALS pathogenesis in vivo

Amyotrophic lateral sclerosis (ALS) also known as Lou Gehrig’s Disease, is a neurodegenerative disease for which there is no effective treatment.

Project ongoing See Project & Researchers
Grant type
Team grants
Area of Research
Neurodegeneration
Competition
ALS Canada - Brain Canada Discovery Grants
Province
Québec
Start Date
2024

Deepening our understanding of G3BP1 and its paralog G3BP2 to facilitate accurate therapeutic development for ALS/FTD

While significant efforts have been made worldwide, the development of an effective therapy to significantly slow or halt ALS disease progression has remained elusive.

Project ongoing See Project & Researchers
Grant type
Team grants
Competition
ALS Canada - Brain Canada Discovery Grants
Province
Québec
Start Date
2023

Investigating the neuronal function of a novel HNRNPA1 variant

While significant efforts have been made worldwide, the development of an effective therapy to significantly slow or halt amyotrophic lateral sclerosis (ALS) progression has remained elusive.

Project ongoing See Project & Researchers
Grant type
Team grants
Area of Research
Neurodegeneration
Competition
ALS Canada - Brain Canada Discovery Grants
Province
Québec
Start Date
2022

Comprehensive Analysis Platform To Understand, Remedy and Eliminate ALS

Amyotrophic lateral sclerosis (ALS) is a terminal disease that paralyzes people because the brain is no longer able to communicate with the muscles that we are typically able to move at will.

Project ongoing See Project & Researchers
Grant type
Platform grants
Area of Research
Neurodegeneration
Competition
2019 Platform Support Grants
Province
Alberta
Start Date
2021