Funded Grants

One of the major challenges facing the BRAIN initiative is the development of technologies that will enable the recording of neural activity throughout the entire volume of a rodent brain.

Stroke is the leading cause of disability among adults and one of the three leading causes of death in North America.

Stroke is the sudden death of brain cells caused by insufficient blood supply to the brain. Parts of the brain that enable us to walk and talk are often damaged most by a stroke.

Stroke is a major cause of death and disability. At present, there are no clear and effective therapies to aid the majority of patients who suffer stroke.

Stroke is a leading cause of adult long term disability and the third leading cause of death in industrialized countries.

In recent years, it was discovered that a microscopic worm called C. elegans could mimic some of the aspects of human ALS when they were engineered to have abnormal (mutant) genes that cause the disease.

In late 2011, a landmark discovery was made which identified that abnormalities (mutation) in a gene called C9ORF72 were responsible for the highest percentage of hereditary ALS and frontotemporal dementia cases.

ALS is a disease characterized by degeneration of both upper and lower motor neurons.

Tissue engineering is a process that was originally designed and continues to be used for growing cells outside the body, turning them into functional tissues and organs, and applying them for clinical use.

One of the hallmarks of ALS is the presence of abnormal clumps inside motor neurons that contain various substances which include, in the majority of cases, something called TAR DNA–binding protein 43 (TDP-43).