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Stroke is a common and disabling brain disorder which may have long-lasting effects.

Because of low fitness and heart problems, people with stroke are at very high risk of a second stroke or heart attack within 10 years.

The first question people ask after suffering a stroke is: “Why?”

The lifetime risk of developing amyotrophic lateral sclerosis (ALS) is approximately 1 in 350 for men and 1 in 440 for women, making it the most common adult-onset motor neuron disease.

Aberrant tRNA processing and function has the capacity to exacerbate misfolding of ALS-associated proteins and the ensuing toxicity.

One in four strokes are caused by a condition called cerebral small vessel disease (CSVD). There are no approved treatments for CSVD.

Ischemic stroke occurs when a person suffers a sudden blockage of an artery in their brain.

Carotid disease accounts for 10% of ischemic strokes and has high rate of recurrence of up to 30%-50%(1, 2).

Atrial fibrillation (AF) is the most common heart rhythm disorder.

Acute ischemic stroke represents the vast majority of strokes.